Automatic Reconstruction of Mitochondria and Endoplasmic Reticulum in Electron Microscopy Volumes by Deep Learning

Automatic Reconstruction of Mitochondria and Endoplasmic Reticulum in Electron Microscopy Volumes by Deep Learning

Together, mitochondria and the endoplasmic reticulum (ER) occupy more than 20% of a cell's volume, and morphological abnormality may lead to cellular function disorders. With the rapid development of large-scale electron microscopy (EM), manual contouring and three-dimensional (3D) reconstructi...

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Bibliographic Details
Main Authors: Jing Liu, Linlin Li, Yang Yang, Bei Hong, Xi Chen, Qiwei Xie, Hua Han
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-07-01
Series:Frontiers in Neuroscience
Subjects:
mitochondria
endoplasmic reticulum
electron microscopes
segmentation
3D reconstruction
Online Access:https://www.frontiersin.org/article/10.3389/fnins.2020.00599/full

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