TLR7 activation by imiquimod worsens glycemic control in female FVB/N mice consuming a high‐fat diet
Abstract Toll‐like receptor‐7 (TLR7) activation promotes autoimmunity, and metabolic syndrome (MetS) is a common comorbidity in patients with autoimmune disease. We previously demonstrated hyperinsulinemia in TLR7 agonist imiquimod (IMQ)‐treated, high‐fat diet (HFD)‐fed female C57BL/6 mice. Since mo...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
Wiley
2024-02-01
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Series: | Physiological Reports |
Subjects: | |
Online Access: | https://doi.org/10.14814/phy2.15949 |