A Novel Analytical Strategy to Identify Fusion Transcripts between Repetitive Elements and Protein Coding-Exons Using RNA-Seq.

A Novel Analytical Strategy to Identify Fusion Transcripts between Repetitive Elements and Protein Coding-Exons Using RNA-Seq.

Repetitive elements (REs) comprise 40-60% of the mammalian genome and have been shown to epigenetically influence the expression of genes through the formation of fusion transcript (FTs). We previously showed that an intracisternal A particle forms an FT with the agouti gene in mice, causing obesity...

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Bibliographic Details
Main Authors: Tianyuan Wang, Janine H Santos, Jian Feng, David C Fargo, Li Shen, Gonzalo Riadi, Elizabeth Keeley, Zachary S Rosh, Eric J Nestler, Richard P Woychik
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4945064?pdf=render

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http://europepmc.org/articles/PMC4945064?pdf=render

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