MicroRNA composition of plasma extracellular vesicles: a harbinger of late cardiotoxicity of doxorubicin

MicroRNA composition of plasma extracellular vesicles: a harbinger of late cardiotoxicity of doxorubicin

Abstract Background The use of doxorubicin is associated with an increased risk of acute and long-term cardiomyopathy. Despite the constantly growing number of cancer survivors, little is known about the transcriptional mechanisms which progress in the time leading to a severe cardiac outcome. It is...

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Main Authors: Justyna Totoń-Żurańska, Joanna Sulicka-Grodzicka, Michał T. Seweryn, Ewelina Pitera, Przemysław Kapusta, Paweł Konieczny, Leszek Drabik, Maria Kołton-Wróż, Bernadeta Chyrchel, Ewelina Nowak, Andrzej Surdacki, Tomasz Grodzicki, Paweł P. Wołkow
Format: Article
Language:English
Published: BMC 2022-12-01
Series:Molecular Medicine
Subjects:
Clinical transcriptomics
Micro-RNAs (miRNAs)
Extracellular vesicles (EVs)
Cardiotoxicity
Doxorubicin
Childhood acute lymphoblastic leukemia (ALL)
Online Access:https://doi.org/10.1186/s10020-022-00588-0

Internet

https://doi.org/10.1186/s10020-022-00588-0

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