VEGF-C-expressing TAMs rewire the metastatic fate of breast cancer cells

Summary: The expression of pro-lymphangiogenic VEGF-C in primary tumors is associated with sentinel lymph node metastasis in most solid cancer types. However, the impact of VEGF-C on distant organ metastasis remains unclear. Perivascular tumor-associated macrophages (TAMs) play a crucial role in gui...

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Bibliographic Details
Main Authors: Kaveri Banerjee, Thomas Kerzel, Tove Bekkhus, Sabrina de Souza Ferreira, Tatjana Wallmann, Majken Wallerius, Laura-Sophie Landwehr, Dennis Alexander Agardy, Nele Schauer, Anna Malmerfeldt, Jonas Bergh, Margarita Bartish, Johan Hartman, Arne Östman, Mario Leonardo Squadrito, Charlotte Rolny
Format: Article
Language:English
Published: Elsevier 2023-12-01
Series:Cell Reports
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S221112472301519X