A glycine-rich PE_PGRS protein governs mycobacterial actin-based motility

Mycobacterium marinum, a close relative of Mycobacterium tuberculosis, polymerizes host actin at the bacterial surface to drive intracellular movement and cell-to-cell spread during infection. Here, Hill & Welch identify an M. marinum surface protein that binds to and activates the host protein...

Full description

Bibliographic Details
Main Authors: Norbert S. Hill, Matthew D. Welch
Format: Article
Language:English
Published: Nature Portfolio 2022-06-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-022-31333-0