Sex and age bias viral burden and interferon responses during SARS-CoV-2 infection in ferrets

Sex and age bias viral burden and interferon responses during SARS-CoV-2 infection in ferrets

Abstract SARS-CoV-2 (Severe Acute Respiratory Syndrome Coronavirus 2) hospitalizations and deaths disportionally affect males and older ages. Here we investigated the impact of male sex and age comparing sex-matched or age-matched ferrets infected with SARS-CoV-2. Differences in temperature regulati...

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Bibliographic Details
Main Authors: Magen E. Francis, Brian Richardson, Una Goncin, Mara McNeil, Melissa Rioux, Mary K. Foley, Anni Ge, Roger D. Pechous, Jason Kindrachuk, Cheryl M. Cameron, Christopher Richardson, Jocelyne Lew, Steven Machtaler, Mark J. Cameron, Volker Gerdts, Darryl Falzarano, Alyson A. Kelvin
Format: Article
Language:English
Published: Nature Portfolio 2021-07-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-93855-9

Internet

https://doi.org/10.1038/s41598-021-93855-9

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