Synchrony between daily rhythms of malaria parasites and hosts is driven by an essential amino acid [version 2; peer review: 2 approved]

Background: Rapid asexual replication of blood stage malaria parasites is responsible for the severity of disease symptoms and fuels the production of transmission forms. Here, we demonstrate that a Plasmodium chabaudi’s schedule for asexual replication can be orchestrated by isoleucine, a metabolit...

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Bibliographic Details
Main Authors: Kimberley F. Prior, Benita Middleton, Alíz T.Y. Owolabi, Mary L. Westwood, Jacob Holland, Aidan J. O'Donnell, Michael J. Blackman, Debra J. Skene, Sarah E. Reece
Format: Article
Language:English
Published: Wellcome 2021-10-01
Series:Wellcome Open Research
Online Access:https://wellcomeopenresearch.org/articles/6-186/v2