Synchrony between daily rhythms of malaria parasites and hosts is driven by an essential amino acid [version 2; peer review: 2 approved]
Background: Rapid asexual replication of blood stage malaria parasites is responsible for the severity of disease symptoms and fuels the production of transmission forms. Here, we demonstrate that a Plasmodium chabaudi’s schedule for asexual replication can be orchestrated by isoleucine, a metabolit...
Main Authors: | Kimberley F. Prior, Benita Middleton, Alíz T.Y. Owolabi, Mary L. Westwood, Jacob Holland, Aidan J. O'Donnell, Michael J. Blackman, Debra J. Skene, Sarah E. Reece |
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Format: | Article |
Language: | English |
Published: |
Wellcome
2021-10-01
|
Series: | Wellcome Open Research |
Online Access: | https://wellcomeopenresearch.org/articles/6-186/v2 |
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