Genetic polymorphism and expression of HSF1 gene is significantly associated with breast cancer in Saudi females.

The transcription factor, heat shock factor 1 (HSF1), influences the expression of heat shock proteins as well as other activities like the induction of tumor suppressor genes, signal transduction pathway, and glucose metabolism. We hypothesized that single nucleotide polymorphisms (SNPs) in HSF1 ge...

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Bibliographic Details
Main Authors: Sahar Almotwaa, Mohamed Elrobh, Huda AbdulKarim, Mohamed Alanazi, Sooad Aldaihan, Jilani Shaik, Maha Arafa, Arjumand Sultan Warsy
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5832201?pdf=render