Treatment with therapeutic anticoagulation is not associated with immunotherapy response in advanced cancer patients

Abstract Background Recent preclinical data suggest that there may be therapeutic synergy between immune checkpoint blockade and inhibition of the coagulation cascade. Here, we investigate whether patients who received immune checkpoint inhibitors (ICI) and were on concomitant anticoagulation (AC) e...

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Bibliographic Details
Main Authors: Paul Johannet, Amelia Sawyers, Nicholas Gulati, Douglas Donnelly, Samuel Kozloff, Yingzhi Qian, Alfredo Floristan, Eva Hernando, Judy Zhong, Iman Osman
Format: Article
Language:English
Published: BMC 2021-01-01
Series:Journal of Translational Medicine
Online Access:https://doi.org/10.1186/s12967-021-02712-w