N-acetylcysteine (NAC) for methamphetamine dependence: A randomised controlled trial

N-acetylcysteine (NAC) for methamphetamine dependence: A randomised controlled trial

Background: Methamphetamine dependence is a significant global health concern for which there are no approved medications. The cysteine prodrug, N-acetylcysteine (NAC), has been found to ameliorate glutamate dysregulation in addiction, and to reduce craving for methamphetamine and other drugs. We ev...

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Main Authors: Rebecca McKetin, Olivia M. Dean, Alyna Turner, Peter J. Kelly, Brendan Quinn, Dan I. Lubman, Paul Dietze, Gregory Carter, Peter Higgs, Barbara Sinclair, David Reid, Amanda L. Baker, Victoria Manning, Nina te Pas, Tamsin Thomas, Ramez Bathish, Dayle K. Raftery, Anna Wrobel, Lucy Saunders, Shalini Arunogiri, Frank Cordaro, Harry Hill, Scott Hall, Philip J. Clare, Mohammadreza Mohebbi, Michael Berk
Format: Article
Language:English
Published: Elsevier 2021-08-01
Series:EClinicalMedicine
Subjects:
Substance-related disorders
Methamphetamine
N-Acetylcysteine
Randomised controlled trials
Glutamate
Mental disorders
Online Access:http://www.sciencedirect.com/science/article/pii/S2589537021002856

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http://www.sciencedirect.com/science/article/pii/S2589537021002856

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