Enzymatic conversion of blood group B kidney prevents hyperacute antibody-mediated injuries in ABO-incompatible transplantation

Enzymatic conversion of blood group B kidney prevents hyperacute antibody-mediated injuries in ABO-incompatible transplantation

Abstract Matching ABO blood group antigens between donors and recipients is critical to prevent hyperacute rejection in kidney transplantation. Enzymatic conversion of blood group antigens to the universal O type presents a promising strategy to overcome barriers in ABO-incompatible kidney transplan...

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Bibliographic Details
Main Authors: Jun Zeng, Ming Ma, Xiaojuan Jiang, Zhengsheng Rao, Dan Huang, Hao Zhang, Saifu Yin, Rong Bao, Haohan Zhang, Zhiling Wang, Hongwei Gao, Feng Gong, Tao Lin, Keqin Zhang, Turun Song
Format: Article
Language:English
Published: Nature Portfolio 2025-02-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-025-56563-w

Internet

https://doi.org/10.1038/s41467-025-56563-w

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