Germline DNA Damage Response Gene Mutations in Localized Prostate Cancer

Germline DNA Damage Response Gene Mutations in Localized Prostate Cancer

<i>Background and Objectives</i>: Germline DNA damage response (DDR) gene mutations correlate with increased prostate cancer (PCa) risk and a more aggressive form of the disease. DDR mutation testing is recommended for metastatic PCa cases, while eligible information about the mutations’...

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Bibliographic Details
Main Authors: Tomas Januskevicius, Ieva Vaicekauskaite, Rasa Sabaliauskaite, Augustinas Matulevicius, Alvydas Vezelis, Albertas Ulys, Sonata Jarmalaite, Feliksas Jankevicius
Format: Article
Language:English
Published: MDPI AG 2023-12-01
Series:Medicina
Subjects:
DNA damage response
germline mutation
localized prostate cancer
next-generation sequencing
Online Access:https://www.mdpi.com/1648-9144/60/1/73

Internet

https://www.mdpi.com/1648-9144/60/1/73

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