Deletion of Foxp3<sup>+</sup> regulatory T cells in genetically targeted mice supports development of intestinal inflammation
<p>Abstract</p> <p>Background</p> <p>Mice lacking Foxp3<sup>+</sup> regulatory T (Treg) cells develop severe tissue inflammation in lung, skin, and liver with premature death, whereas the intestine remains uninflamed. This study aims to demonstrate the impor...
Main Authors: | , , , , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2012-07-01
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Series: | BMC Gastroenterology |
Online Access: | http://www.biomedcentral.com/1471-230X/12/97 |