Deletion of Foxp3<sup>+</sup> regulatory T cells in genetically targeted mice supports development of intestinal inflammation

<p>Abstract</p> <p>Background</p> <p>Mice lacking Foxp3<sup>+</sup> regulatory T (Treg) cells develop severe tissue inflammation in lung, skin, and liver with premature death, whereas the intestine remains uninflamed. This study aims to demonstrate the impor...

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Bibliographic Details
Main Authors: Boehm Franziska, Martin Maria, Kesselring Rebecca, Schiechl Gabriela, Geissler Edward K, Schlitt Hans-Jürgen, Fichtner-Feigl Stefan
Format: Article
Language:English
Published: BMC 2012-07-01
Series:BMC Gastroenterology
Online Access:http://www.biomedcentral.com/1471-230X/12/97