Population genomics of intrapatient HIV-1 evolution

Population genomics of intrapatient HIV-1 evolution

Many microbial populations rapidly adapt to changing environments with multiple variants competing for survival. To quantify such complex evolutionary dynamics in vivo, time resolved and genome wide data including rare variants are essential. We performed whole-genome deep sequencing of HIV-1 popula...

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Bibliographic Details
Main Authors: Fabio Zanini, Johanna Brodin, Lina Thebo, Christa Lanz, Göran Bratt, Jan Albert, Richard A Neher
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2015-12-01
Series:eLife
Subjects:
HIV-1
deep sequencing
evolution
reversion
fitness landscapes
Online Access:https://elifesciences.org/articles/11282

Internet

https://elifesciences.org/articles/11282

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