Trimethylamine N-Oxide: The Good, the Bad and the Unknown

Trimethylamine N-oxide (TMAO) is a small colorless amine oxide generated from choline, betaine, and carnitine by gut microbial metabolism. It accumulates in the tissue of marine animals in high concentrations and protects against the protein-destabilizing effects of urea. Plasma level of TMAO is det...

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Bibliographic Details
Main Authors: Manuel T. Velasquez, Ali Ramezani, Alotaibi Manal, Dominic S. Raj
Format: Article
Language:English
Published: MDPI AG 2016-11-01
Series:Toxins
Subjects:
Online Access:http://www.mdpi.com/2072-6651/8/11/326