NEMO inhibits programmed necrosis in an NFκB-independent manner by restraining RIP1.
TNF can trigger two opposing responses: cell survival and cell death. TNFR1 activates caspases that orchestrate apoptosis but some cell types switch to a necrotic death when treated with caspase inhibitors. Several genes that are required to orchestrate cell death by programmed necrosis have been id...
| Váldodahkkit: | , , , |
|---|---|
| Materiálatiipa: | Artihkal |
| Giella: | English |
| Almmustuhtton: |
Public Library of Science (PLoS)
2012-01-01
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| Ráidu: | PLoS ONE |
| Liŋkkat: | http://europepmc.org/articles/PMC3406058?pdf=render |