Phenotypic Alteration of BMDM In Vitro Using Small Interfering RNA

Phenotypic Alteration of BMDM In Vitro Using Small Interfering RNA

Autologous macrophage transfer is an emerging platform for cell therapy. It is anticipated that conventional macrophage reprogramming based on ex vivo polarization using cytokines and ligands of TLRs may enhance the therapeutic effect. We describe an alternative approach based on small interfering R...

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Bibliographic Details
Main Authors: Noreen Halimani, Mikhail Nesterchuk, Irina N. Andreichenko, Alexandra A. Tsitrina, Andrey Elchaninov, Anastasia Lokhonina, Timur Fatkhudinov, Nataliya O. Dashenkova, Vera Brezgina, Timofei S. Zatsepin, Arsen S. Mikaelyan, Yuri V. Kotelevtsev
Format: Article
Language:English
Published: MDPI AG 2022-08-01
Series:Cells
Subjects:
macrophages
polarization
siRNA
IRF5
IRF3
EGR2
Online Access:https://www.mdpi.com/2073-4409/11/16/2498

Internet

https://www.mdpi.com/2073-4409/11/16/2498

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