Immuno-PET Imaging of Siglec-15 Using the Zirconium-89-Labeled Therapeutic Antibody, NC318
Objective. Sialic acid-binding immunoglobulin-like lectin 15 (Siglec-15) is overexpressed in various cancers which has led to the development of therapeutic anti-Siglec-15 monoconal antibodies (mAbs). In these preclinical studies, the therapeutic mAb, NC318 (antihuman/murine Siglec-15 mAb), was labe...
Main Authors: | , , , , , , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
SAGE Publications
2023-01-01
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Series: | Molecular Imaging |
Online Access: | http://dx.doi.org/10.1155/2023/3499655 |