Raloxifene/SBE-β-CD Inclusion Complexes Formulated into Nanoparticles with Chitosan to Overcome the Absorption Barrier for Bioavailability Enhancement

Raloxifene/SBE-β-CD Inclusion Complexes Formulated into Nanoparticles with Chitosan to Overcome the Absorption Barrier for Bioavailability Enhancement

Raloxifene (RXF) is a hormone-like medication used for treating postmenopausal osteoporosis and estrogen-dependent breast cancer, yet associated with bad low bioavailability due to poor solubility. This study was intended to develop cyclodextrin/chitosan nanoparticles (ccNPs) for oral delivery of RX...

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Bibliographic Details
Main Authors: Zaihua Wang, Yan Li
Format: Article
Language:English
Published: MDPI AG 2018-06-01
Series:Pharmaceutics
Subjects:
raloxifene
bioavailability
nanoparticles
cyclodextrin
chitosan
electrostatic complexation
Online Access:http://www.mdpi.com/1999-4923/10/3/76

Internet

http://www.mdpi.com/1999-4923/10/3/76

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