KATP channel dependent heart multiome atlas

Abstract Plasmalemmal ATP sensitive potassium (KATP) channels are recognized metabolic sensors, yet their cellular reach is less well understood. Here, transgenic Kir6.2 null hearts devoid of the KATP channel pore underwent multiomics surveillance and systems interrogation versus wildtype counterpar...

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Bibliographic Details
Main Authors: D. Kent Arrell, Sungjo Park, Satsuki Yamada, Alexey E. Alekseev, Armin Garmany, Ryounghoon Jeon, Ivan Vuckovic, Jelena Zlatkovic Lindor, Andre Terzic
Format: Article
Language:English
Published: Nature Portfolio 2022-05-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-022-11323-4