Neuronal Oxidative Stress Promotes α-Synuclein Aggregation In Vivo

Neuronal Oxidative Stress Promotes α-Synuclein Aggregation In Vivo

Both genetic and environmental factors increase risk for Parkinson’s disease. Many of the known genetic factors influence α-synuclein aggregation or degradation, whereas most of the identified environmental factors produce oxidative stress. Studies using in vitro approaches have identified mechanism...

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Bibliographic Details
Main Authors: Seok Joon Won, Rebecca Fong, Nicholas Butler, Jennifer Sanchez, Yiguan Zhang, Candance Wong, Olive Tambou Nzoutchoum, Annie Huynh, June Pan, Raymond A. Swanson
Format: Article
Language:English
Published: MDPI AG 2022-12-01
Series:Antioxidants
Subjects:
Parkinson’s disease
cysteine
α-synuclein
oxidative stress
aggregate
proximity ligation assay
Online Access:https://www.mdpi.com/2076-3921/11/12/2466

Internet

https://www.mdpi.com/2076-3921/11/12/2466

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