Elevated plasma level of the glycolysis byproduct methylglyoxal on admission is an independent biomarker of mortality in ICU COVID-19 patients

Elevated plasma level of the glycolysis byproduct methylglyoxal on admission is an independent biomarker of mortality in ICU COVID-19 patients

Abstract Biomarkers to identify ICU COVID-19 patients at high risk for mortality are urgently needed for therapeutic care and management. Here we found plasma levels of the glycolysis byproduct methylglyoxal (MG) were 4.4-fold higher in ICU patients upon admission that later died (n = 33), and 1.7-f...

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Main Authors: Fadhel A. Alomar, Marai N. Alshakhs, Salah Abohelaika, Hassan M. Almarzouk, Mohammed Almualim, Amein K. Al-Ali, Fahad Al-Muhanna, Mohammed F. Alomar, Mousa J. Alhaddad, Mohammed S. Almulaify, Faisal S. Alessa, Ahmed S. Alsalman, Ahmed Alaswad, Sean R. Bidasee, Hassan A. Alsaad, Rudaynah A. Alali, Mona H. AlSheikh, Mohammed S. Akhtar, Mohammed Al Mohaini, Abdulkhaliq J. Alsalman, Hussain Alturaifi, Keshore R. Bidasee
Format: Article
Language:English
Published: Nature Portfolio 2022-06-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-022-12751-y

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https://doi.org/10.1038/s41598-022-12751-y

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