Distinct monocyte subset phenotypes in patients with different clinical forms of chronic Chagas disease and seronegative dilated cardiomyopathy.

Distinct monocyte subset phenotypes in patients with different clinical forms of chronic Chagas disease and seronegative dilated cardiomyopathy.

BACKGROUND:Chronic infection with Trypanosoma cruzi leads to a constant stimulation of the host immune system. Monocytes, which are recruited in response to inflammatory signals, are divided into classical CD14hiCD16-, non-classical CD14loCD16+ and intermediate CD14hiCD16+ subsets. In this study, we...

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Main Authors: Damián E Pérez-Mazliah, Melisa D Castro Eiro, María Gabriela Álvarez, Bruno Lococo, Graciela Bertocchi, Gonzalo César, María A Natale, María C Albareda, Rodolfo Viotti, Susana A Laucella
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-10-01
Series:PLoS Neglected Tropical Diseases
Online Access:http://europepmc.org/articles/PMC6211766?pdf=render

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http://europepmc.org/articles/PMC6211766?pdf=render

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