From structure to function – Ligand recognition by myeloid C-type lectin receptors

From structure to function – Ligand recognition by myeloid C-type lectin receptors

The relevance of protein-glycan interactions in immunity has long been underestimated. Yet, the immune system possesses numerous classes of glycan-binding proteins, so-called lectins. Of specific interest is the group of myeloid C-type lectin receptors (CLRs) as they are mainly expressed by myeloid...

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Bibliographic Details
Main Authors: Swantje Fischer, Felix Stegmann, Vinayaga Srinivasan Gnanapragassam, Bernd Lepenies
Format: Article
Language:English
Published: Elsevier 2022-01-01
Series:Computational and Structural Biotechnology Journal
Subjects:
C-type lectin receptors
Ligand identification
Signaling flexibility
Self-non-self-discrimination
Immune modulation
Host-pathogen interaction
Online Access:http://www.sciencedirect.com/science/article/pii/S2001037022004664

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http://www.sciencedirect.com/science/article/pii/S2001037022004664

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