Inhibitor of Apoptosis (IAP) proteins in pediatric leukemia: Molecular pathways and novel approaches to therapy
Inhibitor of Apoptosis (IAP) proteins are a family of proteins with antiapoptotic functions that contribute to the evasion of apoptosis, a form of programmed cell death. IAP proteins are expressed at high levels in a variety of human cancers including childhood acute leukemia. This elevated expressi...
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Format: | Article |
Language: | English |
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Frontiers Media S.A.
2014-01-01
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Series: | Frontiers in Oncology |
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Online Access: | http://journal.frontiersin.org/Journal/10.3389/fonc.2014.00003/full |