Inhibitor of Apoptosis (IAP) proteins in pediatric leukemia: Molecular pathways and novel approaches to therapy

Inhibitor of Apoptosis (IAP) proteins are a family of proteins with antiapoptotic functions that contribute to the evasion of apoptosis, a form of programmed cell death. IAP proteins are expressed at high levels in a variety of human cancers including childhood acute leukemia. This elevated expressi...

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Bibliographic Details
Main Author: Simone eFulda
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-01-01
Series:Frontiers in Oncology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fonc.2014.00003/full

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