Economic evaluation of using polygenic risk score to guide risk screening and interventions for the prevention of type 2 diabetes in individuals with high overall baseline risk

Type 2 diabetes (T2D) with increasing prevalence is a significant global public health challenge. Obesity, unhealthy diet, and low physical activity are one of the major determinants of the rise in T2D prevalence. In addition, family history and genetic risk of diabetes also play a role in the proce...

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Bibliographic Details
Main Authors: Janne Martikainen, Aku-Ville Lehtimäki, Kari Jalkanen, Piia Lavikainen, Teemu Paajanen, Heidi Marjonen, Kati Kristiansson, Jaana Lindström, Markus Perola
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-09-01
Series:Frontiers in Genetics
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fgene.2022.880799/full