Dengue viral RNA levels in peripheral blood mononuclear cells are associated with disease severity and preexisting dengue immune status.

Infection with dengue viruses (DENV) causes a wide range of manifestations from asymptomatic infection to a febrile illness called dengue fever (DF), to dengue hemorrhagic fever (DHF). The in vivo targets of DENV and the relation between the viral burden in these cells and disease severity are not k...

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Bibliographic Details
Main Authors: Anon Srikiatkhachorn, Sineewanlaya Wichit, Robert V Gibbons, Sharone Green, Daniel H Libraty, Timothy P Endy, Francis A Ennis, Siripen Kalayanarooj, Alan L Rothman
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3526575?pdf=render