Type 1 diabetes and diet-induced obesity predispose C57BL/6J mice to PM2.5-induced lung injury: a comparative study

Type 1 diabetes and diet-induced obesity predispose C57BL/6J mice to PM2.5-induced lung injury: a comparative study

Abstract Background Pre-existing metabolic diseases may predispose individuals to particulate matter (PM)-induced adverse health effects. However, the differences in susceptibility of various metabolic diseases to PM-induced lung injury and their underlying mechanisms have yet to be fully elucidated...

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Bibliographic Details
Main Authors: Shen Chen, Miao Li, Rui Zhang, Lizhu Ye, Yue Jiang, Xinhang Jiang, Hui Peng, Ziwei Wang, Zhanyu Guo, Liping Chen, Rong Zhang, Yujie Niu, Michael Aschner, Daochuan Li, Wen Chen
Format: Article
Language:English
Published: BMC 2023-04-01
Series:Particle and Fibre Toxicology
Subjects:
Type 1 diabetes
High-fat diet
Particulate matter
Lung injury
RNA sequencing
Xenobiotic metabolism
Online Access:https://doi.org/10.1186/s12989-023-00526-w

Internet

https://doi.org/10.1186/s12989-023-00526-w

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