A Low Affinity GCaMP3 Variant (GCaMPer) for Imaging the Endoplasmic Reticulum Calcium Store.

A Low Affinity GCaMP3 Variant (GCaMPer) for Imaging the Endoplasmic Reticulum Calcium Store.

Endoplasmic reticulum calcium homeostasis is critical for cellular functions and is disrupted in diverse pathologies including neurodegeneration and cardiovascular disease. Owing to the high concentration of calcium within the ER, studying this subcellular compartment requires tools that are optimiz...

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Bibliographic Details
Main Authors: Mark J Henderson, Heather A Baldwin, Christopher A Werley, Stefano Boccardo, Leslie R Whitaker, Xiaokang Yan, Graham T Holt, Eric R Schreiter, Loren L Looger, Adam E Cohen, Douglas S Kim, Brandon K Harvey
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4599735?pdf=render

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http://europepmc.org/articles/PMC4599735?pdf=render

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