Differential Functional Contribution of BK Channel Subunits to Aldosterone-Induced Channel Activation in Vascular Smooth Muscle and Eventual Cerebral Artery Dilation

Differential Functional Contribution of BK Channel Subunits to Aldosterone-Induced Channel Activation in Vascular Smooth Muscle and Eventual Cerebral Artery Dilation

Calcium/voltage-activated potassium channels (BK) control smooth muscle (SM) tone and cerebral artery diameter. They include channel-forming α and regulatory β<sub>1</sub> subunits, the latter being highly expressed in SM. Both subunits participate in steroid-induced modification of BK a...

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Bibliographic Details
Main Authors: Steven C. Mysiewicz, Sydney M. Hawks, Anna N. Bukiya, Alex M. Dopico
Format: Article
Language:English
Published: MDPI AG 2023-05-01
Series:International Journal of Molecular Sciences
Subjects:
microscale thermophoresis
patch-clamp
steroids
MaxiK channel
<i>KCNMB1</i>
vascular smooth muscle
Online Access:https://www.mdpi.com/1422-0067/24/10/8704

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https://www.mdpi.com/1422-0067/24/10/8704

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