NTRK Gene Fusion Detection in Atypical Spitz Tumors

NTRK Gene Fusion Detection in Atypical Spitz Tumors

Atypical Spitz tumors (AST) deviate from stereotypical Spitz nevi for one or more atypical features and are now regarded as an intermediate category of melanocytic tumors with uncertain malignant potential. Activating <i>NTRK1/NTRK3</i> fusions elicit oncogenic events in Spitz lesions an...

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Bibliographic Details
Main Authors: Rocco Cappellesso, Filippo Nozzoli, Federica Zito Marino, Sara Simi, Francesca Castiglione, Vincenzo De Giorgi, Carlo Cota, Rebecca Senetta, Giosuè Scognamiglio, Anna Maria Anniciello, Anna Maria Cesinaro, Mario Mandalà, Andrea Gianatti, Maria Gabriella Valente, Barbara Valeri, Angela Rita Sementa, Costantino Ricci, Barbara Corti, Giandomenico Roviello, Angelo Paolo Dei Tos, Renato Franco, Daniela Massi
Format: Article
Language:English
Published: MDPI AG 2021-11-01
Series:International Journal of Molecular Sciences
Subjects:
atypical spitz tumor
<i>NTRK</i>
<i>NTRK1</i>
<i>NTRK3</i>
pan-TRK
Online Access:https://www.mdpi.com/1422-0067/22/22/12332

Internet

https://www.mdpi.com/1422-0067/22/22/12332

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