Diabetic nephropathy patients show hyper-responsiveness to N6-carboxymethyllysine

Diabetic nephropathy patients show hyper-responsiveness to N6-carboxymethyllysine

The aim of this study was to evaluate the impact of N6-carboxymethyllysine (CML) on NF-κB gene expression and tumor necrosis factor (TNF) production in diabetic nephropathy. This was an observational study comprised of three groups: diabetic nephropathy (n=30), type II diabetes mellitus (n=28), and...

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Bibliographic Details
Main Authors: C.G. Dias, L. Venkataswamy, S. Balakrishna
Format: Article
Language:English
Published: Associação Brasileira de Divulgação Científica 2022-07-01
Series:Brazilian Journal of Medical and Biological Research
Subjects:
Diabetic nephropathy
Receptor for advanced glycation end-product pathway
N6-carboxymethyllysine
Nuclear factor-kappa B
Tumor necrosis factor
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2022000100648&tlng=en

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http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2022000100648&tlng=en

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