Brassinin Induces Apoptosis, Autophagy, and Paraptosis via MAPK Signaling Pathway Activation in Chronic Myelogenous Leukemia Cells

Brassinin Induces Apoptosis, Autophagy, and Paraptosis via MAPK Signaling Pathway Activation in Chronic Myelogenous Leukemia Cells

Brassinin (BSN), a potent phytoalexin found in cruciferous vegetables, has been found to exhibit diverse anti-neoplastic effects on different cancers. However, the impact of BSN on chronic myelogenous leukemia (CML) cells and the possible mode of its actions have not been described earlier. We inves...

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Bibliographic Details
Main Authors: Min Hee Yang, In Jin Ha, Seok-Geun Lee, Junhee Lee, Jae-Young Um, Gautam Sethi, Kwang Seok Ahn
Format: Article
Language:English
Published: MDPI AG 2023-02-01
Series:Biology
Subjects:
brassinin
apoptosis
autophagy
paraptosis
mitogen-activated protein kinase (MAPK)
chronic myelogenous leukemia (CML)
Online Access:https://www.mdpi.com/2079-7737/12/2/307

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https://www.mdpi.com/2079-7737/12/2/307

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