Excessive nitrite affects zebrafish valvulogenesis through yielding too much NO signaling.

Sodium nitrite, a common food additive, exists widely not only in the environment but also in our body. Excessive nitrite causes toxicological effects on human health; however, whether it affects vertebrate heart valve development remains unknown. In vertebrates, developmental defects of cardiac val...

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Bibliographic Details
Main Authors: Junbo Li, Wenshuang Jia, Qingshun Zhao
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3962429?pdf=render