Keratin-mediated hair growth and its underlying biological mechanism

Injecting human hair-derived keratin into mice skin accelerates hair growth & formation, as TGFβ2 secretion during hair destruction stimulates epithelial cell death and keratin release, leading to dermal cell condensation & hair growth.

Bibliographic Details
Main Authors: Seong Yeong An, Hyo-Sung Kim, So Yeon Kim, Se Young Van, Han Jun Kim, Jae-Hyung Lee, Song Wook Han, Il Keun Kwon, Chul-Kyu Lee, Sun Hee Do, Yu-Shik Hwang
Format: Article
Language:English
Published: Nature Portfolio 2022-11-01
Series:Communications Biology
Online Access:https://doi.org/10.1038/s42003-022-04232-9