Computational Modeling of Electrophysiology and Pharmacotherapy of Atrial Fibrillation: Recent Advances and Future Challenges

Computational Modeling of Electrophysiology and Pharmacotherapy of Atrial Fibrillation: Recent Advances and Future Challenges

The pathophysiology of atrial fibrillation (AF) is broad, with components related to the unique and diverse cellular electrophysiology of atrial myocytes, structural complexity, and heterogeneity of atrial tissue, and pronounced disease-associated remodeling of both cells and tissue. A major challen...

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Bibliographic Details
Main Authors: Márcia Vagos, Ilsbeth G. M. van Herck, Joakim Sundnes, Hermenegild J. Arevalo, Andrew G. Edwards, Jussi T. Koivumäki
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-09-01
Series:Frontiers in Physiology
Subjects:
atrial fibrillation
computational modeling
drug therapies
in silico drug screening
pathophysiology
pharmacology
Online Access:https://www.frontiersin.org/article/10.3389/fphys.2018.01221/full

Internet

https://www.frontiersin.org/article/10.3389/fphys.2018.01221/full

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