Calibrating Hepatitis E Virus Serological Assays Using Asymptomatic Specimens Obtained in Japan

Calibrating Hepatitis E Virus Serological Assays Using Asymptomatic Specimens Obtained in Japan

ABSTRACT This study aimed to calibrate hepatitis E virus (HEV) serological assays. We optimized the previously developed in-house HEV antibody enzyme-linked immunosorbent assay (ELISA) by setting the cutoff with an in-house serological performance panel consisting of broad HEV antibody titers and su...

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Bibliographic Details
Main Authors: Kazutaka Terahara, Tian-Cheng Li, Keiji Matsubayashi, Hidekatsu Sakata, Takanobu Kato, Atsushi Naganuma, Koji Ogawa, Koichi Honda, Jun Itakura, Noriyuki Akutsu, Hiroshi Tobita, Masaaki Korenaga, Tatsuya Kanto, Ryuichi Sugiyama, Ryosuke Suzuki, Isao Hamaguchi, Masanori Isogawa, Yoshimasa Takahashi
Format: Article
Language:English
Published: American Society for Microbiology 2022-10-01
Series:Microbiology Spectrum
Subjects:
ELISA
HEV
IgA
IgM
immunoserology
Online Access:https://journals.asm.org/doi/10.1128/spectrum.02146-22

Internet

https://journals.asm.org/doi/10.1128/spectrum.02146-22

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