Single-cell and Bulk RNA-Seq reveal angiogenic heterogeneity and microenvironmental features to evaluate prognosis and therapeutic response in lung adenocarcinoma

Single-cell and Bulk RNA-Seq reveal angiogenic heterogeneity and microenvironmental features to evaluate prognosis and therapeutic response in lung adenocarcinoma

BackgroundAngiogenesis stands as a pivotal hallmark in lung adenocarcinoma (LUAD), intricately shaping the tumor microenvironment (TME) and influencing LUAD progression. It emerges as a promising therapeutic target for LUAD, affecting patients’ prognosis. However, its role in TME, LUAD prognosis, an...

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Bibliographic Details
Main Authors: Lijuan Tang, Zhike Chen, Jian Yang, Qifan Li, Sichu Wang, Taoming Mo, Weibiao Zeng, Hao Ding, Shu Pan
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-02-01
Series:Frontiers in Immunology
Subjects:
angiogenesis
tumor microenvironment
immune infiltration
immune therapy
prognosis
lung adenocarcinoma
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2024.1352893/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2024.1352893/full

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