Multi-Parameter Quantitative Imaging of Tumor Microenvironments Reveals Perivascular Immune Niches Associated With Anti-Tumor Immunity

Multi-Parameter Quantitative Imaging of Tumor Microenvironments Reveals Perivascular Immune Niches Associated With Anti-Tumor Immunity

Tumors are populated by a multitude of immune cell types with varied phenotypic and functional properties, which can either promote or inhibit anti-tumor responses. Appropriate localization and function of these cells within tumors is critical for protective immunity, with CD8 T cell infiltration be...

Full description

Bibliographic Details
Main Authors: Caleb R. Stoltzfus, Ramya Sivakumar, Leo Kunz, Brandy E. Olin Pope, Elena Menietti, Dario Speziale, Roberto Adelfio, Marina Bacac, Sara Colombetti, Mario Perro, Michael Y. Gerner
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-08-01
Series:Frontiers in Immunology
Subjects:
spatial analysis
quantitative microscopy
tumor microenvironments
CD8 T cells
dendritic cells
macrophages
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.726492/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2021.726492/full

Similar Items