Multi-Parameter Quantitative Imaging of Tumor Microenvironments Reveals Perivascular Immune Niches Associated With Anti-Tumor Immunity

Multi-Parameter Quantitative Imaging of Tumor Microenvironments Reveals Perivascular Immune Niches Associated With Anti-Tumor Immunity

Tumors are populated by a multitude of immune cell types with varied phenotypic and functional properties, which can either promote or inhibit anti-tumor responses. Appropriate localization and function of these cells within tumors is critical for protective immunity, with CD8 T cell infiltration be...

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Bibliographic Details
Main Authors:	Caleb R. Stoltzfus, Ramya Sivakumar, Leo Kunz, Brandy E. Olin Pope, Elena Menietti, Dario Speziale, Roberto Adelfio, Marina Bacac, Sara Colombetti, Mario Perro, Michael Y. Gerner
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2021-08-01
Series:	Frontiers in Immunology
Subjects:	spatial analysis quantitative microscopy tumor microenvironments CD8 T cells dendritic cells macrophages
Online Access:	https://www.frontiersin.org/articles/10.3389/fimmu.2021.726492/full

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