A multiplex blood-based assay targeting DNA methylation in PBMCs enables early detection of breast cancer

A multiplex blood-based assay targeting DNA methylation in PBMCs enables early detection of breast cancer

Abstract The immune system can monitor tumor development, and DNA methylation is involved in the body’s immune response to tumors. In this work, we investigate whether DNA methylation alterations in peripheral blood mononuclear cells (PBMCs) could be used as markers for early detection of breast can...

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Bibliographic Details
Main Authors: Tiantian Wang, Peilong Li, Qiuchen Qi, Shujun Zhang, Yan Xie, Jing Wang, Shibiao Liu, Suhong Ma, Shijun Li, Tingting Gong, Huiting Xu, Mengqiu Xiong, Guanghua Li, Chongge You, Zhaofan Luo, Juan Li, Lutao Du, Chuanxin Wang
Format: Article
Language:English
Published: Nature Portfolio 2023-08-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-023-40389-5

Internet

https://doi.org/10.1038/s41467-023-40389-5

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