Ciliary tip actin dynamics regulate photoreceptor outer segment integrity

Ciliary tip actin dynamics regulate photoreceptor outer segment integrity

Abstract As signalling organelles, cilia regulate their G protein-coupled receptor content by ectocytosis, a process requiring localised actin dynamics to alter membrane shape. Photoreceptor outer segments comprise an expanse of folded membranes (discs) at the tip of highly-specialised connecting ci...

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Bibliographic Details
Main Authors: Roly Megaw, Abigail Moye, Zhixian Zhang, Fay Newton, Fraser McPhie, Laura C. Murphy, Lisa McKie, Feng He, Melissa K. Jungnickel, Alex von Kriegsheim, Peter A. Tennant, Chloe Brotherton, Christine Gurniak, Alecia K. Gross, Laura M. Machesky, Theodore G. Wensel, Pleasantine Mill
Format: Article
Language:English
Published: Nature Portfolio 2024-05-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-024-48639-w

Internet

https://doi.org/10.1038/s41467-024-48639-w

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