Down-regulation of CDH1 is associated with expression of SNAI1 in colorectal adenomas.

Down-regulation of E-cadherin (CDH1) and epithelial-mesenchymal transition (EMT) are considered critical events for invasion and metastasis of colorectal carcinoma. Here we tested whether the important regulators of E-cadherin expression SNAI1 and TWIST1 are already detectable in human colorectal ad...

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Bibliographic Details
Main Authors: Feride Kroepil, Georg Fluegen, Zaurbek Totikov, Stephan E Baldus, Christian Vay, Matthias Schauer, Stefan A Topp, Jan Schulte Am Esch, Wolfram T Knoefel, Nikolas H Stoecklein
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3460919?pdf=render