Ketone Administration for Seizure Disorders: History and Rationale for Ketone Esters and Metabolic Alternatives

The ketogenic diet (KD) is a high-fat, low-carbohydrate treatment for medically intractable epilepsy. One of the hallmark features of the KD is the production of ketone bodies which have long been believed, but not yet proven, to exert direct anti-seizure effects. The prevailing view has been that k...

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Bibliographic Details
Main Authors: Angela M. Poff, Jong M. Rho, Dominic P. D’Agostino
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-10-01
Series:Frontiers in Neuroscience
Subjects:
Online Access:https://www.frontiersin.org/article/10.3389/fnins.2019.01041/full