Spatial transcriptomics delineates molecular features and cellular plasticity in lung adenocarcinoma progression

Abstract Indolent (lepidic) and aggressive (micropapillary, solid, and poorly differentiated acinar) histologic subtypes often coexist within a tumor tissue of lung adenocarcinoma (LUAD), but the molecular features associated with different subtypes and their transitions remain elusive. Here, we com...

Full description

Bibliographic Details
Main Authors: Yan Wang, Bing Liu, Qingjie Min, Xin Yang, Shi Yan, Yuanyuan Ma, Shaolei Li, Jiawen Fan, Yaqi Wang, Bin Dong, Huajing Teng, Dongmei Lin, Qimin Zhan, Nan Wu
Format: Article
Language:English
Published: Nature Publishing Group 2023-09-01
Series:Cell Discovery
Online Access:https://doi.org/10.1038/s41421-023-00591-7