Mutations in JAK/STAT and NOTCH1 Genes Are Enriched in Post-Transplant Lymphoproliferative Disorders

Mutations in JAK/STAT and NOTCH1 Genes Are Enriched in Post-Transplant Lymphoproliferative Disorders

Post-transplant lymphoproliferative disorders (PTLD) are diseases occurring in immunocompromised patients after hematopoietic stem cell transplantation (HCT) or solid organ transplantation (SOT). Although PTLD occurs rarely, it may be associated with poor outcomes. In most cases, PTLD is driven by E...

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Bibliographic Details
Main Authors: Alexandra Butzmann, Kaushik Sridhar, Diwash Jangam, Hanbing Song, Amol Singh, Jyoti Kumar, Karen M. Chisholm, Benjamin Pinsky, Franklin Huang, Robert S. Ohgami
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-01-01
Series:Frontiers in Oncology
Subjects:
PTLD
Epstein-Barr Virus (EBV)
florid follicular hyperplasia
targeted sequencing
next generation (deep) sequencing (NGS)
whole transcriptome sequencing
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2021.790481/full

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https://www.frontiersin.org/articles/10.3389/fonc.2021.790481/full

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