The Npa1p complex chaperones the assembly of the earliest eukaryotic large ribosomal subunit precursor.

The early steps of the production of the large ribosomal subunit are probably the least understood stages of eukaryotic ribosome biogenesis. The first specific precursor to the yeast large ribosomal subunit, the first pre-60S particle, contains 30 assembly factors (AFs), including 8 RNA helicases. T...

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Bibliographic Details
Main Authors: Clément Joret, Régine Capeyrou, Kamila Belhabich-Baumas, Célia Plisson-Chastang, Rabea Ghandour, Odile Humbert, Sébastien Fribourg, Nicolas Leulliot, Simon Lebaron, Anthony K Henras, Yves Henry
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-08-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC6136799?pdf=render